Benefits of using locoregional analgesia

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During an interview with dvm360 discussing his previous lecture at the Fetch Kansas City Conference in Missouri, Gianluca Bini, DVM, MRCVS, DACVAA, explains the benefits of using locoregional analgesia when it comes to preventing chronic pain in patients compared to using systemic analgesics such as opioids.

Below is a partial transcript

Gianluca Bini, DVM, MRCVS, DACVAA: The primary benefits, you know, the pain pathway, it's made of different steps, right? So you have your transduction, which is basically when the painful stimuli gets changed into an electrical signal. Your peripheral nerves will transmit that signal from the area it's impacted to the spinal and in the spinal cord, there is another piece of the pathway that's called modulation, and that's where potentially chronic pain may develop, right? And so even if we do use systemic energetics like your opioids or alpha-2 agonists or your ketamine, for example, all those analgesics may still unfortunately trigger chronic pain in that patient, because the stimulus did reach the spinal cord. When you perform a local anesthesia...you perform your nerve blocks, what you do is you actually cut the transmission, like blowing up a bridge right?