Case 11

Because you are concerned that Rintu is not continuing to respond to traditional therapy with methocarbamol, and in an effort to expedite clearance of the toxin rather than just continue symptomatic treatment, you discuss extra-label ILE therapy with Rintu's owners. You explain that, while more in-depth, placebo-controlled studies are needed, case reports and anecdotal reports of ILE therapy in dogs and cats have demonstrated success. Potential side effects of the treatment include hypersensitivity reactions due to the egg stabilizer in the emulsion and thrombophlebitis at the catheter site.

The owners consent to ILE therapy, so you discontinue the crystalloid fluids to begin the infusion. The suggested protocol is 1.5 ml/kg of 20% ILE solution given intravenously as a bolus over one minute, followed by 0.25 ml/kg/min given as a constant-rate infusion (CRI) over one to two hours.

QUESTION 6

Based on the above protocol, you calculate Rintu will need an initial bolus of 7.5 ml of lipid emulsion given intravenously over one minute, followed by 1.25 ml/min given as a CRI for one to two hours. So it is appropriate to begin the infusion, true or false?

True

False

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