Equine Medicine

Equine Cushings Disease (Pituitary Pars Intermedia Dysfunction [PPID]) is a disorder that likely affects more than half the population of horses aged 14 years and older. If unmanaged, affected horses are at risk for laminitis and insulin resistance (IR) and are immune-suppressed, increasing their risk of numerous infections.

Fermentation in the hindgut of the horse is similar to that in the rumen, resulting in the production of short-chain volatile fatty acids mainly acetic, propionic and butyric acids. The proportions of these acids are influenced by the availability and type of substrate, composition of the microbial community and the hindgut physiologic conditions.

Equine infectious diseases continue to emerge and re-emerge, infecting horses across the US and beyond. For the purpose of this discussion, we will discuss equine piroplasmosis (EP), methicillin-resistant Staphylococcus aureus, and Lyme Disease in the horse.

Sperm quality is the culmination of a variety of factors such as the total sperm number, sperm motility, sperm morphology, and sperm fertilizing ability. Presently in an assessment of the quality of a stallion's ejaculate, it is often based only on the volume, motility, and concentration of the sperm. These are relatively easy parameters to quantify.

Neonatal isoerythrolysis occurs when the foal inherits blood antigens (types) from the stallion that are different from that of the mare. As a result, the mare may produce antibodies to these antigens, which are then concentrated in her colostrum.

High risk mares are mares that are at significant risk of problems during pregnancy. This includes mares that are of advanced age, repeated history of unsuccessful foaling outcomes, mares with twin pregnancies, mares that have experienced a significant toxemia, or that suffer significant physical infirmaries including chronic founder, severe arthritis, or body wall injuries or mares that have placentitis,.

Endometritis is the most common infectious pathologic condition affecting the uterus in brood mares. Pathologic endometritis is an abnormal extension of a physiologic process. In the pathologic form excessive inflammation of the endometrium occurs and then persists.

Equine gastric ulcer syndrome (EGUS) is common in performance horses and in foals. Diagnosis of EGUS is based on history, clinical signs, endoscopic examination, and response to treatment. All ages and breeds of horses are susceptible to EGUS and current therapeutic strategies focus on blocking gastric acid secretion and raising stomach pH.

Reproductive problems of stallions occur frequently and may be related to physiologic, pathologic, and management processes. Relatively few colts are kept as stallions in the equine industry, and veterinarians may not have a great deal of exposure or experience with stallions.

Endoscopic examination of the mare's uterus is primarily used as tool to aid in the diagnosis of unusual conditions, such as intractable infections, tumors, abscesses, foreign bodies, adhesions, and congenital abnormalities.

One of the critical functions of the reticular formation of the brainstem is activation of the cerebral cortex for the awake state. This component of the formation, known as the ascending reticular activating system (ARAS), is an ill-defined meshwork of cells concentrated in the rostral brainstem that receives afferent input from all parts of the CNS and projects excitatory stimuli cortically.

The brainstem includes the diencephalon, mesencephalon (midbrain), and rhombencephalon (hindbrain). With the exception of the olfactory nerves (I), all cranial nerves are arrayed along the brainstem. The hindbrain is divided into metencephalon (cerebellum) and myelencephalon (pons and medulla oblongata).

Axons of the upper motor neuron (UMN) extrapyramidal and vestibular systems travel from cell bodies throughout the brain and pass predominantly in reticulospinal and vestibulospinal tracts to lower motor neurons (LMN) in the ventral and intermediate columns of the gray matter of the spinal cord.

Fungi are eukaryotic organisms with a cell wall made up of chitins, glucans and mannans. The plasma membrane contains ergosterol, which is a sterol that is targeted by several antifungal drugs. Fungal infections in horses are relatively uncommon, although geographic prevalence is highly variable.

The term "wobbler" or "wobbler syndrome" describes a group of developmental anomalies and degenerative conditions involving the cervical vertebrae of ataxic horses (Hahn et al. 1999; Mayhew 2009). Several more or less descriptive abbreviations are used in wobbler terminology.

Clostridial myositis results from rapidly progressive necrosis of muscle from infection with clostridial organisms, often with fatal consequences. The majority of equine cases are secondary to intramuscular injections or as a result of direct contamination of deep wounds with bacterial growth in an anaerobic environment.

Deciding when to refer a horse with colic can be a difficult decision and involves careful evaluation of clinical and laboratory parameters, surgical considerations, probability of survival, and other considerations that include worsening of clinical condition, unresolved pain, or to obtain a second opinion.

Diagnosis and treatment of horses with colic have certainly improved in the last 20 years. However, horses with recurrent colic continue to be a diagnostic and often management challenge for both owners and veterinarians.

New information cerebellar abiotrophy of Arabians, Severe Combined Immunodeficieincy (SCID) of Arabians, Lavender foal syndrome of Arabians, Lethal White Syndrome of overo Paints, Glycogen Branching Enzyme Deficiency (GBED) of Quarter Horses, hemophila and thrombobasthenia will be discussed.

If the foal is less than 12 hours, it can be given 1-3 liters of high quality (sp gr > 1.090) colostrum. (Frozen colostrum should be thawed in warm water, rather than the microwave. Ideally colostrum should be < 12 months old).

Equine colitis can be a diagnostic and therapeutic challenge for both practitioners and owners alike. The presenting clinical signs can be identical regardless of the etiology.

Strangles is a result of bacterial infection with Streptococcus equi subspecies equi (referred to as S. equi). The disease has been in the equine population for centuries and was first reported in 1251 (Sweeney et al, 2005i). The infection is highly contagious in horse populations and can become endemic on farms with previous outbreaks of the disease.

Recurrent airway obstruction (also known as heaves, chronic bronchitis, chronic obstructive pulmonary disease, broken wind, and chronic airway reactivity) is a common respiratory disease of horses characterized by periods of reversible airway obstruction caused by neutrophil accumulation, mucus production, and bronchospasm.

Diarrhea is a significant cause of morbidity and mortality in foals. Numerous noninfectious and infectious agents are responsible for enterocolitis and enteritis in the newborn foal.

Unlike EGUS, colonic ulcers and the condition Right Dorsal Colitis (RDC) occur less frequently, but may lead to hypoproteinemia and more severe clinical signs. In a necroscopic study of 545 horses, 44% of non-performance horses and 65% of the performance horses had colonic ulcers.

Veterinarians are often asked to induce parturition or they may recommend induction based on the mare's foaling history or the presence of medical conditions that threaten her health and well being. The need to induce a mare, and the chances of foal survival should be based on objective measures.

Equine protozoal myeloencephalitis (EPM) is a common neurological disease of horses in the Americas. Horses with EPM most commonly have abnormalities of gait but also may present with signs of brain disease.

As the weather heats up, so does the incidence of heat exhaustion and heat stroke in horses.

Targeted horse husbandry and evolution has produced an elite equine athlete capable of attaining fast speeds and exercising over long distances.

What should practitioners consider when evaluating and recommending nutritional supplements for equine patients?