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The pathophysiology of DIC: When the hemostatic system malfunctions
September 1st 2005Disseminated intravascular coagulation (DIC), also known as consumptive coagulopathy or defibrination syndrome, is an acquired disorder of the hemostatic system that results in the pathologic activation and disequilibria of normal hemostasis and fibrinolysis, leading to potentially fatal consequences. This syndrome is common in critically ill veterinary patients and is always secondary to an underlying disorder that increases systemic thrombin and plasmin activities.